{"id":7813,"date":"2025-03-02T15:00:57","date_gmt":"2025-03-02T05:00:57","guid":{"rendered":"https:\/\/www.drseragyoussif.com.au\/?page_id=7813"},"modified":"2025-03-02T15:46:05","modified_gmt":"2025-03-02T05:46:05","slug":"overleap","status":"publish","type":"page","link":"https:\/\/www.drseragyoussif.com.au\/?page_id=7813","title":{"rendered":"Overleap"},"content":{"rendered":"
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Overleap<\/span><\/h2>\n<\/div>\n<\/div>\n<\/div>\n
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Ovaleap <\/strong><\/p>\n

patient leaflet, side effects, dosage<\/span><\/p>\n

Contains active substance :<\/span><\/p>\n

follitropin alfa ()<\/span><\/p>\n

ATC code:<\/span><\/p>\n

G03GA05 follitropin alfa<\/span><\/p>\n

Patient leaflet<\/span><\/p>\n

Summary of medicine characteristics<\/strong><\/p>\n

Table of contents<\/span><\/p>\n

1. What Ovaleap is and what it is used for<\/span><\/p>\n

2. What you need to know before you use Ovaleap<\/span><\/p>\n

3. How to use Ovaleap<\/span><\/p>\n

4. Possible side effects<\/span><\/p>\n

5. How to store Ovaleap<\/span><\/p>\n

6. Contents of the pack and other information<\/span><\/p>\n

<\/p>\n

Patient leaflet – Ovaleap<\/span><\/p>\n

 <\/span><\/p>\n

– If you get any side effects, talk to your doctor, pharmacist or nurse. This includes any possible side effects not listed in this<\/span><\/p>\n

leaflet.<\/span><\/p>\n

<\/p>\n

What is in this leaflet<\/span><\/p>\n

<\/p>\n

1. What Ovaleap is and what it is used for<\/span><\/p>\n

<\/p>\n

2. What you need to know before you use Ovaleap<\/span><\/p>\n

<\/p>\n

3. How to use Ovaleap<\/span><\/p>\n

<\/p>\n

4. Possible side effects<\/span><\/p>\n

<\/p>\n

5. How to store Ovaleap<\/span><\/p>\n

<\/p>\n

6. Contents of the pack and other information<\/span><\/p>\n

<\/p>\n

1. What Ovaleap is and what it is used for<\/span><\/p>\n

What Ovaleap is<\/span><\/p>\n

<\/p>\n

This medicine contains the active substance follitropinalfa, which is almost identical to a natural hormone produced by your body called \u201cfollicle-stimulating hormone\u201d (FSH). FSH is a gonadotropin, a type of hormone that plays an important role in human fertility and reproduction. In women, FSH is needed for the growth and development of the sacs (follicles) in the ovaries that contain the egg cells. In men, FSH is needed for the production of sperm.<\/span><\/p>\n

<\/p>\n

What Ovaleap is used for<\/span><\/p>\n

<\/p>\n

In adult women, Ovaleap is used:<\/span><\/p>\n

<\/p>\n

to help ovulation (release of a mature egg cell from the follicle) in women that cannot ovulate and that have not responded to treatment with a medicine called \u201cclomifene citrate\u201d.<\/span><\/p>\n

to help follicles develop in women undergoing assisted reproductive technology procedures (procedures that may help you to become pregnant) such as \u201cin vitro fertilisation\u201d, \u201cgamete intra-fallopian transfer\u201d or \u201czygote intra-fallopian transfer\u201d.<\/span><\/p>\n

in combination with a medicine called \u201clutropin alfa\u201d (a version of another gonadotropin, \u201cluteinising hormone\u201d or LH) to help ovulation in women that are not ovulating because their body is producing too little FSH and LH.<\/span><\/p>\n

<\/span><\/p>\n

In adult men, Ovaleap is used:<\/span><\/p>\n

<\/p>\n

in combination with a medicine called \u201chuman chorionic gonadotropin\u201d (hCG) to help produce sperm in men that are infertile due to low levels of certain hormones.<\/span><\/p>\n

<\/span><\/p>\n

2. What you need to know before you use Ovaleap<\/span><\/p>\n

<\/span><\/p>\n

Do not use Ovaleap:<\/span><\/p>\n

<\/p>\n

if you are allergic to follitropin alfa, Follicle Stimulating Hormone (FSH) or any of the other ingredients of this medicine (listed in section 6).<\/span><\/p>\n

if you have a tumour in your hypothalamus or pituitary gland (parts of the brain).<\/span><\/p>\n

if you are a woman with:<\/span><\/p>\n

\u2013 large ovaries or sacs of fluids within the ovaries (ovarian cysts) of unknown origin.<\/span><\/p>\n

\u2013 unexplained vaginal bleeding.<\/span><\/p>\n

\u2013 cancer in your ovaries, womb or breasts.<\/span><\/p>\n

\u2013 any condition that usually makes normal pregnancy impossible, such as ovarian failure (early menopause), fibroid tumours of the womb or malformed reproductive organs.<\/span><\/p>\n

<\/p>\n

if you are a man with:<\/span><\/p>\n

\u2013 testicular failure that is not treatable.<\/span><\/p>\n

<\/p>\n

Do not use this medicine if any of the above applies to you.<\/span><\/p>\n

<\/span><\/p>\n

If you are not sure, talk to your doctor or pharmacist before using this medicine.<\/span><\/p>\n

<\/p>\n

Warnings and precautions<\/span><\/p>\n

<\/p>\n

Before the treatment is started you and your partner\u2019s fertility should be evaluated by a doctor experienced in treating fertility disorders.<\/span><\/p>\n

<\/p>\n

Porphyria Tell your doctor before you start treatment, if you or any member of your family have porphyria. This is a condition that may be passed on<\/span><\/p>\n

from parents to children which means that you have an inability to break down porphyrins (organic compounds).<\/span><\/p>\n

<\/p>\n

Tell your doctor straight away if:<\/span><\/p>\n

<\/p>\n

your skin becomes fragile and easily blistered, especially skin that has been frequently in the sun, and\/or you have stomach, arm or leg pain.<\/span><\/p>\n

If you experience the above symptoms your doctor may recommend that you stop treatment.<\/span><\/p>\n

<\/p>\n

Ovarian Hyper-Stimulation Syndrome (OHSS)<\/span><\/p>\n

<\/p>\n

If you are a woman, this medicine increases your risk of developing OHSS. This is when your follicles develop too much and become large cysts.<\/span><\/p>\n

<\/p>\n

Talk to your doctor straight away if:<\/span><\/p>\n

<\/p>\n

you get pain in the lower part of the abdomen (belly),<\/span><\/p>\n

you gain any weight rapidly,<\/span><\/p>\n

you feel sick or ar vomiting,<\/span><\/p>\n

you have difficulty in breathing.<\/span><\/p>\n

If you experience the above symptoms your doctor might ask you to stop using this medicine (see also section 4 under \u201cSerious side<\/span><\/p>\n

effects in women”).<\/span><\/p>\n

<\/p>\n

If you are not ovulating and if the recommended dose and timing are followed, the occurrence of OHSS is less likely. Ovaleap treatment seldom causes severe OHSS unless the medicine that is used for final follicular maturation (containing human chorionic gonadotropin, hCG) is given. If you are developing OHSS your doctor may not give you any hCG in this treatment cycle.<\/span><\/p>\n

You may be told not to have sex or to use a barrier contraceptive method for at least 4 days.<\/span><\/p>\n

<\/p>\n

Multiple pregnancy<\/span><\/p>\n

<\/p>\n

When using this medicine, you have a higher risk of being pregnant with more than one child (i.e. \u201cmultiple pregnancy\u201d, typically twins) than if you conceived naturally. Multiple pregnancy may lead to medical complications for you and your babies. You can reduce the risk of multiple pregnancy by using the right dose of this medicine at the right times. When undergoing assisted reproductive technology the risk of having a multiple pregnancy is related to your age, the quality and number of fertilised eggs or embryos placed inside you.<\/span><\/p>\n

<\/p>\n

Miscarriage<\/span><\/p>\n

<\/p>\n

You are more likely to have a miscarriage than the average woman when undergoing assisted reproductive technology or stimulation of your ovaries to produce eggs.<\/span><\/p>\n

<\/p>\n

Ectopic pregnancy<\/span><\/p>\n

<\/p>\n

You are more likely to have a pregnancy outside the womb (an ectopic pregnancy) than the average woman when undergoing assisted reproductive<\/span><\/p>\n

technology and if you have damaged fallopian tubes.<\/span><\/p>\n

<\/p>\n

Birth defects<\/span><\/p>\n

<\/p>\n

When being conceived by assisted reproductive technology, a baby may have a slightly higher risk of birth defects than after natural conception. This could be related to multiple pregnancies or to parent characteristics such as maternal age and sperm characteristics.<\/span><\/p>\n

<\/p>\n

Blood clotting problems (thromboembolic events)<\/span><\/p>\n

<\/p>\n

If you have ever had blood clots in your leg or lung, or a heart attack or stroke, or if your family have experienced these, inform your doctor. You might have a higher risk of these problems occurring or becoming worse with Ovaleap treatment.<\/span><\/p>\n

<\/p>\n

Men with too much FSH in their blood<\/span><\/p>\n

<\/p>\n

If you are a man, having too much natural FSH in your blood can be a sign of damaged testicles. This medicine usually does not work if you<\/span><\/p>\n

have this problem. If your doctor decides to try Ovaleap treatment, they may monitor it by asking you to provide semen for analysis 4 to 6 months<\/span><\/p>\n

after starting treatment.<\/span><\/p>\n

<\/p>\n

Children and adolescents<\/span><\/p>\n

<\/p>\n

This medicine is not indicated for use in children and adolescents less than 18 years of age.<\/span><\/p>\n

<\/p>\n

Other medicines and Ovaleap<\/span><\/p>\n

<\/p>\n

Tell your doctor or pharmacist if you are using, have recently used or might use any other medicines.<\/span><\/p>\n

<\/p>\n

If you use Ovaleap with other medicines which help ovulation such as human chorionic gonadotropin (hCG) or clomifene citrate, this may increase the response of your follicles.<\/span><\/p>\n

If you use Ovaleap at the same time as a \u201cgonadotropin-releasing hormone\u201d (GnRH) agonist or antagonist (these medicines<\/span><\/p>\n

reduce your sex hormone levels and stop you ovulating) you may need a higher dose of Ovaleap to produce follicles.<\/span><\/p>\n

<\/span><\/p>\n

Pregnancy and breast-feeding<\/span><\/p>\n

You should not use this medicine if you are pregnant or breast-feeding.<\/span><\/p>\n

<\/p>\n

Driving and using machines<\/span><\/p>\n

<\/p>\n

This medicine does not affect your ability to drive and use machines.<\/span><\/p>\n

<\/p>\n

Ovaleap contains sodium, benzalkonium chloride and benzyl alcohol<\/span><\/p>\n

<\/p>\n

This medicine contains less than 1 mmol sodium (23 mg) per dose, that is to say essentially \u2018sodium-free\u2019.<\/span><\/p>\n

<\/p>\n

This medicine also contains 0.02 mg per mL of benzalkonium chloride and 10.0 mg per mL of benzyl alcohol. Ask your doctor or pharmacist for advice if you have a liver or kidney disease, and if you are pregnant or breast-feeding. This is because large amounts of benzylvalcohol can build-up in your body and may cause side effects (called \u201cmetabolic acidosis\u201d).<\/span><\/p>\n

<\/p>\n

3. How to use Ovaleap<\/span><\/p>\n

Always use this medicine exactly as your doctor or pharmacist has told you. Check with your doctor or pharmacist if you are not sure.<\/span><\/p>\n

<\/p>\n

This medicine is given as an injection into the tissue just under the skin (subcutaneous injection). Your doctor or nurse will show you how to inject the medicine. If you administer this medicine to yourself, please carefully read and follow the \u201cInstructions for Use\u201d of the pen.<\/span><\/p>\n

<\/p>\n

What the recommended dose is<\/span><\/p>\n

<\/p>\n

Your doctor will decide how much medicine you will take and how often. The doses described below are stated in International Units (IU).<\/span><\/p>\n

<\/p>\n

Women<\/span><\/p>\n

<\/p>\n

If you are not ovulating and have irregular or no periods<\/span><\/p>\n

<\/p>\n

This medicine is usually given every day.<\/span><\/p>\n

If you have irregular periods, start using this medicine within the first 7 days of your menstrual cycle. If you do not have periods, you can start using the medicine on any convenient day.<\/span><\/p>\n

The usual starting dose of this medicine is 75 to 150 IU each day.<\/span><\/p>\n

Your dose of this medicine may be increased every 7 or every 14 days by 37.5 to 75 IU, until you get the desired response.<\/span><\/p>\n

<\/p>\n

The maximum daily dose of this medicine is usually not higher than 225 IU.<\/span><\/p>\n

When you get the desired response, you will be given hCG or \u201crecombinant hCG\u201d (r-hCG, anvhCG made in a laboratory by a special DNA technique). The<\/span><\/p>\n

single injection will be 250 micrograms of r-hCG or 5,000 to 10,000 IU of hCG, 24 to 48 hours after your last Ovaleap injection. The best time to have sex is on the day of the hCG injection and the day after. Alternatively, intrauterine insemination may be performed by placing the sperm into the womb cavity.<\/span><\/p>\n

<\/p>\n

If your doctor cannot see a desired response after 4 weeks, that treatment cycle with Ovaleap should be stopped. For the following treatment cycle, your doctor will give you a higher starting dose of this medicine than before.<\/span><\/p>\n

<\/p>\n

If your body responds too strongly, your treatment will be stopped and you will not be given any hCG [see also section 2 under<\/span><\/p>\n

\u201cOvarian Hyper-Stimulation Syndrome (OHSS)\u201d]. For the following cycle, your doctor will give you a lower dose of Ovaleap than before.<\/span><\/p>\n

<\/p>\n

If you need to develop several eggs for collection prior to any assisted reproductive technology<\/span><\/p>\n

<\/p>\n

The usual starting dose of this medicine is 150 to 225 IU each day, from day 2 or 3 of your menstrual cycle.<\/span><\/p>\n

The dose may be increased, depending on your response. The maximum daily dose is 450 IU.<\/span><\/p>\n

Treatment is continued until your eggs have developed to a desired point. This usually takes about 10 days but can take any time between 5 and<\/span><\/p>\n

20 days. Your doctor will use blood tests and\/or an ultrasound machine to check when this is.<\/span><\/p>\n

<\/p>\n

When your eggs are ready, you will be given hCG or r-hCG. The single injection will be 250 micrograms of r-hCG or 5,000 to 10,000 IU of hCG, 24 to 48 hours after the last Ovaleap injection. This gets your eggs ready for collection.<\/span><\/p>\n

In other cases, your doctor may first stop you from ovulating by using a gonadotropin-releasing hormone (GnRH) agonist or antagonist. Then Ovaleap is given approximately 2 weeks after the start of agonist treatment. The Ovaleap and GnRH agonist are then both given until your follicles develop as desired.<\/span><\/p>\n

<\/p>\n

If you are not ovulating, have no periods and have been diagnosed with very low levels of FSH and LH hormones<\/span><\/p>\n

<\/p>\n

The usual starting dose of Ovaleap is 75 to 150 IU together with 75 IU of lutropin alfa.<\/span><\/p>\n

You will use these two medicines each day for up to 5 weeks.<\/span><\/p>\n

Your dose of Ovaleap may be increased every 7 or every 14 days by 37.5 to 75 IU, until you get the desired response.<\/span><\/p>\n

When you get the desired response, you will be given hCG or r-hCG. The single injection will be 250 micrograms of r-hCG or 5,000 to 10,000 IU of hCG, 24 to 48 hours after your last injections of Ovaleap and lutropin alfa. The best time to have sex is on the day of the hCG injection and the day after. Alternatively, intrauterine insemination may be performed by placing the sperm into the womb cavity.<\/span><\/p>\n

If your doctor cannot see a response after 5 weeks, that treatment cycle should be stopped. For the following cycle, your doctor<\/span><\/p>\n

will give you a higher starting dose of this medicine than before.<\/span><\/p>\n

<\/p>\n

If your body responds too strongly, your treatment with Ovaleap will be stopped and you will not be given any hCG [see also section 2 under \u201cOvarian Hyper-Stimulation Syndrome (OHSS)\u201d]. For the following cycle, your doctor will give you a lower dose of Ovaleap than before.<\/span><\/p>\n

<\/p>\n

Men<\/span><\/p>\n

<\/p>\n

The usual dose of this medicine is 150 IU together with hCG. You will use these two medicines three times a week for at least 4 months.<\/span><\/p>\n

If you have not responded to treatment after 4 months, your doctor may suggest that you continue using these two medicines for at<\/span><\/p>\n

least 18 months.<\/span><\/p>\n

<\/span><\/p>\n

How are the injections given?<\/span><\/p>\n

<\/p>\n

This medicine is given as an injection into the tissue just<\/span><\/p>\n

under the skin (subcutaneous injection) using the Ovaleap Pen. The Ovaleap Pen<\/span><\/p>\n

is a device (a \u201cpen\u201d) used for giving injections into the tissue just under<\/span><\/p>\n

the skin.<\/span><\/p>\n

<\/p>\n

Your doctor may suggest that you learn how to inject<\/span><\/p>\n

yourself with this medicine. Your doctor or nurse will give you instructions on<\/span><\/p>\n

how to do this and you can also find instructions in the separate instructions<\/span><\/p>\n

for use of the pen. Do not attempt to self-administer this medicine without<\/span><\/p>\n

this training by your doctor or nurse. The very first injection of this<\/span><\/p>\n

medicine should only be given in the presence of a doctor or nurse.<\/span><\/p>\n

<\/p>\n

Ovaleap solution for injection in cartridges has been<\/span><\/p>\n

developed for use in the Ovaleap Pen. You must follow the separate instructions<\/span><\/p>\n

for use of the Ovaleap Pen carefully. The instructions for use of the pen will<\/span><\/p>\n

be provided together with the Ovaleap Pen. Proper treatment of your condition,<\/span><\/p>\n

however, requires close and constant co-operation with your doctor.<\/span><\/p>\n

<\/p>\n

Discard used needles immediately after injection.<\/span><\/p>\n

<\/p>\n

If you use more Ovaleap than you should<\/span><\/p>\n

<\/p>\n

The effects of using too much Ovaleap are unknown.<\/span><\/p>\n

Nevertheless one could expect Ovarian Hyper-Stimulation Syndrome (OHSS) to<\/span><\/p>\n

occur, which is described in section 4 under \u201cSerious side effects in<\/span><\/p>\n

women”. However, the OHSS will only occur if hCG is also administered [see<\/span><\/p>\n

also section 2 under \u201cOvarian Hyper-Stimulation Syndrome (OHSS)\u201d].<\/span><\/p>\n

<\/p>\n

If you forget to use Ovaleap<\/span><\/p>\n

<\/p>\n

Do not use a double dose to make up for a forgotten dose.<\/span><\/p>\n

Please talk to your doctor as soon as you realise that you forgot a dose.<\/span><\/p>\n

<\/p>\n

If you have any further questions on the use of this<\/span><\/p>\n

medicine, ask your doctor, pharmacist or nurse.<\/span><\/p>\n

<\/p>\n

4. Possible side effects<\/span><\/p>\n

Like all medicines, this medicine can cause side effects,<\/span><\/p>\n

although not everybody gets them.<\/span><\/p>\n

<\/p>\n

Important side effects<\/span><\/p>\n

<\/p>\n

Serious side effects in men and women<\/span><\/p>\n

<\/p>\n

Allergic reactions such as skin rash, raised itchy areas of<\/span><\/p>\n

skin and severe allergic reactions with weakness, drop in blood pressure,<\/span><\/p>\n

difficulty breathing and swelling of the face have been reported very rarely<\/span><\/p>\n

(may affect up to 1 in 10,000 people). If you think you are having<\/span><\/p>\n

this type of reaction, you must stop your Ovaleap injection and get medical<\/span><\/p>\n

help immediately.<\/span><\/p>\n

Serious side effects in women<\/span><\/p>\n

<\/p>\n

Lower stomach ache together with nausea or vomiting may be<\/span><\/p>\n

the symptoms of Ovarian Hyper-Stimulation Syndrome (OHSS). This may indicate<\/span><\/p>\n

that the ovaries over-reacted to the treatment and that large ovarian cysts<\/span><\/p>\n

developed [see also section 2 under \u201cOvarian Hyper-Stimulation Syndrome<\/span><\/p>\n

(OHSS)\u201d]. This side effect is common (may affect up to 1 in<\/span><\/p>\n

10 people).<\/span><\/p>\n

OHSS may become severe with clearly enlarged ovaries,<\/span><\/p>\n

decreased urine production, weight gain, difficulty in breathing and\/or<\/span><\/p>\n

possible fluid accumulation in your stomach or chest. This side effect is<\/span><\/p>\n

uncommon (may affect up to 1 in 100 people).<\/span><\/p>\n

Complications of OHSS such as twisting of ovaries or blood<\/span><\/p>\n

clotting may occur rarely (may affect up to 1 in 1,000 people).<\/span><\/p>\n

Serious blood clotting complications (thromboembolic<\/span><\/p>\n

events), sometimes independent of OHSS, may be found very rarely (may affect up<\/span><\/p>\n

to 1 in 10,000 people). This could cause chest pain, breathlessness,<\/span><\/p>\n

stroke or heart attack [see also section 2 under \u201cBlood clotting problems<\/span><\/p>\n

(thromboembolic events)\u201d].<\/span><\/p>\n

If you notice any of the above-listed side effects you<\/span><\/p>\n

should immediately contact your doctor who may ask you to stop using Ovaleap.<\/span><\/p>\n

<\/p>\n

Other side effects in women<\/span><\/p>\n

<\/p>\n

Very common (may affect more than 1 in 10 people)<\/span><\/p>\n

<\/p>\n

Local reactions at the injection site, such as pain,<\/span><\/p>\n

redness, bruising, swelling and\/or irritation<\/span><\/p>\n

Headache<\/span><\/p>\n

Sacs of fluid within the ovaries (ovarian cysts)<\/span><\/p>\n

Common (may affect up to 1 in 10 people)<\/span><\/p>\n

<\/p>\n

Stomach ache<\/span><\/p>\n

Abdominal bloating<\/span><\/p>\n

Abdominal cramps<\/span><\/p>\n

Feeling sick<\/span><\/p>\n

Vomiting<\/span><\/p>\n

Diarrhoea<\/span><\/p>\n

Very rare (may affect up to 1 in 10,000 people)<\/span><\/p>\n

<\/p>\n

Your asthma may get worse.<\/span><\/p>\n

Other side effects in men<\/span><\/p>\n

<\/p>\n

Very common (may affect more than 1 in 10 people)<\/span><\/p>\n

<\/p>\n

Local reactions at the injection site, such as pain,<\/span><\/p>\n

redness, bruising, swelling and\/or irritation Common (may affect up to<\/span><\/p>\n

1 in 10 people)<\/span><\/p>\n

Swelling of the veins above and behind the testicles (a<\/span><\/p>\n

varicocele)<\/span><\/p>\n

Breast development<\/span><\/p>\n

Acne<\/span><\/p>\n

Weight gain<\/span><\/p>\n

Very rare (may affect up to 1 in 10,000 people)<\/span><\/p>\n

<\/p>\n

Your asthma may get worse.<\/span><\/p>\n

Reporting of side effects<\/span><\/p>\n

<\/p>\n

If you get any side effects, talk to your doctor, pharmacist<\/span><\/p>\n

or nurse. This includes any possible side effects not listed in this leaflet.<\/span><\/p>\n

You can also report side effects directly via the national reporting system<\/span><\/p>\n

listed in Appendix V.. By reporting side effects you can help provide more<\/span><\/p>\n

information on the safety of this medicine.<\/span><\/p>\n

<\/p>\n

5. How to store Ovaleap<\/span><\/p>\n

Keep this medicine out of the sight and reach of children.<\/span><\/p>\n

<\/p>\n

Do not use this medicine after the expiry date which is<\/span><\/p>\n

stated on the label and outer carton after EXP. The expiry date refers to the<\/span><\/p>\n

last day of that month.<\/span><\/p>\n

<\/p>\n

Store in a refrigerator (2 \u00b0C \u2013 8 \u00b0C).<\/span><\/p>\n

<\/p>\n

Do not freeze.<\/span><\/p>\n

<\/p>\n

Keep the cartridge in the outer carton in order to protect<\/span><\/p>\n

from light.<\/span><\/p>\n

<\/p>\n

Before opening and within its shelf life, you may remove<\/span><\/p>\n

this medicine from the refrigerator, without being refrigerated again, for up<\/span><\/p>\n

to 3 months. Do not store above 25 \u00b0C. You must discard this medicine<\/span><\/p>\n

if it has not been used after 3 months.<\/span><\/p>\n

<\/p>\n

Once opened, the cartridge in-use in the pen may be stored<\/span><\/p>\n

for a maximum of 28 days. Do not store above 25 \u00b0C. Write down the<\/span><\/p>\n

date of first use in the patient diary, which will be provided with the<\/span><\/p>\n

Ovaleap Pen.<\/span><\/p>\n

<\/p>\n

Put the pen cap back on the Ovaleap Pen after each injection<\/span><\/p>\n

in order to protect the cartridge from light.<\/span><\/p>\n

<\/p>\n

Do not use this medicine if you notice it is cloudy or there<\/span><\/p>\n

are particles in it.<\/span><\/p>\n

<\/p>\n

Do not throw away any medicines via wastewater. Ask your<\/span><\/p>\n

pharmacist how to throw away medicines you no longer use. These measures will<\/span><\/p>\n

help protect the environment.<\/span><\/p>\n

<\/p>\n

 Source:<\/span><\/p>\n

https:\/\/patient-info.co.uk\/ovaleap-70934\/patient-leaflet<\/span><\/p>\n<\/div>\n<\/div>\n<\/div>\n

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Overleap Ovaleap patient leaflet, side effects, dosage Contains active substance : follitropin alfa () ATC code: G03GA05 follitropin alfa Patient leaflet Summary of medicine characteristics Table of contents 1. What Ovaleap is and what it is used for 2. What you need to know before you use Ovaleap 3. How to use Ovaleap 4. Possible… Continue reading Overleap<\/span><\/a><\/p>\n","protected":false},"author":1,"featured_media":0,"parent":6441,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"brizy-blank-template.php","meta":{"footnotes":""},"class_list":["post-7813","page","type-page","status-publish","hentry","entry"],"_links":{"self":[{"href":"https:\/\/www.drseragyoussif.com.au\/index.php?rest_route=\/wp\/v2\/pages\/7813","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.drseragyoussif.com.au\/index.php?rest_route=\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/www.drseragyoussif.com.au\/index.php?rest_route=\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/www.drseragyoussif.com.au\/index.php?rest_route=\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.drseragyoussif.com.au\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=7813"}],"version-history":[{"count":12,"href":"https:\/\/www.drseragyoussif.com.au\/index.php?rest_route=\/wp\/v2\/pages\/7813\/revisions"}],"predecessor-version":[{"id":7987,"href":"https:\/\/www.drseragyoussif.com.au\/index.php?rest_route=\/wp\/v2\/pages\/7813\/revisions\/7987"}],"up":[{"embeddable":true,"href":"https:\/\/www.drseragyoussif.com.au\/index.php?rest_route=\/wp\/v2\/pages\/6441"}],"wp:attachment":[{"href":"https:\/\/www.drseragyoussif.com.au\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=7813"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}